Cafe Au Lait Spots Causes

This gene is believed to function as a tumor suppressor.

Cafe au lait spots causes. Visible signs of neurofibromatosis such as extensive cafe au lait spots many neurofibromas in the facial area or large neurofibromas can cause anxiety and emotional distress even if they re not medically serious. Café au lait spots are often harmless but. Cafe au lait spots are themselves benign and do not cause any illness or problems. They are also called giraffe spots or coast of maine spots which refers to their jagged borders.

Café au lait also referred to as café au lait spots or café au lait macules present as well circumscribed evenly pigmented macules and patches that range in size from 1 to 2 mm to greater than 20 cm in greatest diameter. Cafe au lait spots causes the brown color of a cafe au lait macule is due to a pigment called melanin which is produced in the skin by cells called melanocytes. However those related to nf1 are caused by an increased proliferation of melanocytes. Yes cafe au lait spots causes complications if it is not treated.

Café au lait spots or café au lait macules are flat pigmented birthmarks. This is known as epidermal melanotic hypermelanosis. However they may be associated with syndromes such as neurofibromatosis type 1 and mccune albright syndrome. Café au lait spots aren t a type of rash or an allergic reaction so these spots don t itch or cause pain.

Risk of high blood pressure. Below is the list of complications and problems that may arise if cafe au lait spots is left untreated. Click to read full answer. They are caused by a collection of pigment producing melanocytes in the epidermis of the skin.

These spots are typically permanent and may grow or increase in number over time. In about 50 percent of people with nf1 the disorder results from gene mutations that occur for unknown reasons spontaneous mutation. Nf1 is caused by mutations in the gene that controls production of a protein called neurofibromin neurofibromin 1. Developing a spot on your body can be a cause for concern but café au lait spots are.

Café au lait spots macules are caused by an excessive production of melanosomes by a normal number of pigment producing cells melanocytes. The epidermal melanocytes of an isolated cafe au lait macule have excessive numbers of melanosomes intracellular pigment granules. The name café au lait is french for coffee with milk and refers to their light brown color.