Cafe Au Lait Spots Neurofibromatosis Type 1

Actualización sobre los criterios dermatológicos diagnósticos de la enfermedad.

Cafe au lait spots neurofibromatosis type 1. An update on neurofibromatosis type 1. Not just café au lait spots freckling and neurofibromas. The most common symptom of nf1 is the appearance of painless coffee coloured patches on the skin called café au lait spots. Más que manchas café con leche efélides y neurofibromas.

Anin content occurs in melanocytes cultured from café au lait spots s34. During childhood most children with nf1 will have at least 6 café au lait spots. Solitary café au lait spots are quite common in the general population but multiple café au lait macules calm are often indicative of an underlying genetic disorder. It sounds like 2 of the spots meet the measurement criteria for a cafe au lait spot but the diagnostic criteria for nf1 is 6 or more café au lait spots larger that 5 cm in children.

I know it can be frustrating to take a wait and see approach especially with a little baby. The spots can be present at birth or develop by the time a child is 3 years old. It is noteworthy that like cutaneous neurofibromas café au lait. However not everyone with café au lait spots has nf1.

The etiopathogenesis of these macules is still very obscure. Although previous studies reported that almost individuals with multiple café au lait macules will eventually develop nf1 based on clinical criteria recent studies and clinical observations suggest that a significant percentage of them do not have nf1. Dermatological clinical criteria diagnostic of the disease neurofibromatosis tipo 1.